The Vibrio Pathogenicity Island-Encoded Mop Protein Modulates the Pathogenesis and Reactogenicity of Epidemic Vibrio cholerae
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چکیده
منابع مشابه
The vibrio pathogenicity island-encoded mop protein modulates the pathogenesis and reactogenicity of epidemic vibrio cholerae.
Epidemic Vibrio cholerae possess the VPI (Vibrio pathogenicity island) essential virulence gene cluster. The VPI is 41.2 kb in size and encodes 29 potential proteins, several of which have no known function. We show that the VPI-encoded Orf4 is a predicted 34-kDa periplasmic protein containing a zinc metalloprotease motif. V. cholerae seventh-pandemic (El Tor) strain N16961 carrying an orf4 mut...
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sensitive strain P3343110. When tested by long PCR, all 20 S. Java isolates produced a 10,041-bp fragment identical to that produced by P3170700. PCR was used to determine whether the pentaresistant phenotype was due to the presence of the Salmonella genomic island 1 (SGI1) as previously described (5). All 20 strains produced amplicons with primers U7-L12 and LJ-R1 for the left junction and pri...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2003
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.71.1.510-515.2003